A postdoctoral position is available to solve protein structures using modern NMR methods. Research focus is to elucidate the structure and dynamics of a unique class of cell-to-cell membrane fusion proteins or fragments using hetero- and homonuclear multidimensional gradient NMR techniques. This project utilizes a baculovirus expression system to over-express isotopically labelled post-translationally modified proteins. For some additional information visit http://myweb.dal.ca/rsyvitsk/Research/index.html.
Candidates who are competent in multidimensional heteronuclear NMR methods, solving macromolecular structure, pulse program development, and have a keen interest in learning to solve structures are preferred. Familiarity with protein expression and purification would be an advantage. Highly qualified candidates are encouraged to apply for a Killam Post-Doctoral Fellowship (www.dalgrad.dal.ca/killam/kpdf ).
This laboratory, part of a newly established Structural Biology collaboration between Dalhousie and the National Research Council, is equipped with two state-of-the-art 500 MHz spectrometers, a 700 MHz solid-state spectrometer and modern facilities for high resolution/accuracy MS, protein chemistry, biochemistry, and computation. In addition we have access to the National 800 MHz spectrometers in Montreal and the NANUC facility in Edmonton. Application by e-mail is preferred. Please send a CV, delineating your specific role in each publication described, with the names, addresses, and e-mail contact details of two references to either:
Dr. Ray Syvitski
Functional Macromolecular NMR Research Officer
NRC Institute for Marine Biosciences
Dr. David Jakeman
Associate Professor, College of Pharmacy and Department of Chemistry